Research Interests

My research interests focus on understanding the biological bases of learning and memory. I am interested in applying fMRI techniques to the study of human memory. I am also interested in how memory is affected by injury, disease, and aging.

Publications

Smith, C. N., Bayley, P. J. and Squire, L. R. (in press). Amnesia: Declarative and Nondeclarative Memory. In: Larry R. Squire (Ed.). New Encyclopedia of Neuroscience. Elsevier.

Smith, C. N. Hopkins, R. O., & Squire, L. R. (2006) Experience-dependent eye movements, awareness, and hippocampus-dependent memory. Journal of Neuroscience, 26(44), 11304-11312. [PDF]

Cheng, D. T., Knight, D. C., Smith, C. N., & Helmstetter, F. J. (2006). Human amygdala activity during the expression of fear responses. Behavioral Neuroscience, 120(6), 1187-95. [PDF]

Gold, J. J., Smith, C. N., Bayley, P. J., Shrager, Y., Brewer, J. B., Stark, C. E. L., Hopkins, R. O., Squire, L. R. (2006). Item memory, source memory, and the medial temporal lobe: Concordant findings from fMRI and memory-impaired patients. Proceedings of the National Academy of Sciences, 103(24), 9351-9356. [PDF]

Smith, C. N. & Squire, L. R. (2005). Declarative memory, awareness, and transitive inference. Journal of Neuroscience, 25(44), 10138-46. [PDF]

Smith, C. N., Clark , R. E., Manns, J. R., & Squire, L. R. (2005). Acquisition of differential delay eyeblink classical conditioning is independent of awareness. Behavioral Neuroscience, 119(1), 78-86. [PDF]

Knight, D. C., Cheng, D. T, Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2004). Human amygdala and hippocampal activity during acquisition and extinction of fear conditioning. Cognitive, Affective, and Behavioral Neuroscience, 4(3), 317-25. [PDF]

Knight, D. C., Cheng, D. T, Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2004). Neural substrates mediating human delay and trace fear conditioning. Journal of Neuroscience, 24(1), 218-28. [PDF]

Cheng, D. T., Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2003). Functional MRI of human amygdala activity during pavlovian fear conditioning, stimulus processing versus response expression. Behavioral Neuroscience, 11(1), 1-12. [PDF]

Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (1999). Functional MRI of human pavlovian fear conditioning: Patterns of activation as a function of learning. Neuroreport, 10, 3665-3670. [PDF]

Curriculum Vitae

Place of Birth

San Diego, CA

A. Education

B. A., University of Puget Sound , May 1996, Major: Psychology

M. S., University of Wisconsin-Milwaukee , December 1999, Major: Psychology

Ph. D., University of Wisconsin-Milwaukee , May 2003, Major: Psychology

B. Professional Positions

Teaching Assistant, University of Wisconsin-Milwaukee, Half-time 1996-2000

Research Assistant, University of Wisconsin-Milwaukee, Full-time (summers) 1998-1999

Research Assistant, University of Wisconsin-Milwaukee, Full-time 2001-2003

Postdoctoral Fellow, University of California-San Diego, Full-time 2003-2007

Assistant Project Scientist, University of California-San Diego, Full-time 2007-present

C. Membership in Professional Associations

American Psychological Association (Member)

American Psychological Society (Member)

Society for Neuroscience (Member)

Cognitive Neuroscience Society (Member)

D. Awards

Associated Graduate Students in Psychology Travel Award 2000, 2001, 2002

University of Wisconsin-Milwaukee Graduate Student Travel Award 2000, 2002

Graduate School Summer Research Assistantship for Dissertation Research 2002

American Psychological Association Dissertation Fellowship 2002

Cognitive Neuroscience Postdoctoral Fellowship (NIH) May 2003-June 2005

Neuroplasticity of Aging Postdoctoral Fellowship (NIH) July 2005-June 2006

Dartmouth Summer Institute in Cognitive Neuroscience July 2006

Alzheimer’s Disease Research Center Pilot Project Grant (NIH) April 2007-March 2008

E. Presentations

University of California , San Diego Psychiatry Research Symposium 2007 - The Neuroanatomy of Recent and Remote Semantic Memory: Evidence from Memory-Impaired Patients and Neuroimaging

University of California , San Diego Neurobiology Department Neuro-Dinner 2006 - Eye Movements Index Awareness of Declarative (Conscious) Memory

University of California , San Diego Psychiatry Research Symposium 2006 - Eye Movements Index Awareness of Declarative (Conscious) Memory

Invited Guest Speaker, Ponce School of Medicine, Puerto Rico 2004 - Awareness, Declarative Memory, and the Medial Temporal Lobe

Cognitive Neuroscience Fellows Meeting 2003 - Awareness, Declarative Memory, and the Medial Temporal Lobe

Society for Neuroscience Oral Presentation 2002 - Changes in Stimulus- and Response-Related Networks During Acquisition and Reversal of Fear Conditioning.

Cognitive Neuroscience Brown Bag Presentation, University of Wisconsin-Milwaukee 2002 - Partial Least Squares Analysis of Acquisition and Reversal of Fear Conditioning in Humans

Biophysics Brown Bag Presentation, Medical College of Wisconsin 2001 - Implicit and Explicit Evidence of Fear Conditioning Using fMRI

University of Wisconsin-Milwaukee Graduate Student Symposium 2001 - Network analysis of human differential fear conditioning

Society for Neuroscience Oral Presentation 2000 - Network Analysis of Human Differential Fear Conditioning

University of Wisconsin-Milwaukee Graduate Student Symposium 1999 - Functional Neuroimaging of Human Differential Fear Conditioning

Biophysics Brown Bag Presentation, Medical College of Wisconsin 1998 - Functional Neuroimaging of Human Differential Fear Conditioning

F. Publications

Smith, C. N., Bayley, P. J. and Squire, L. R. (in press). Amnesia: Declarative and Nondeclarative Memory. In: Larry R. Squire (Ed.). New Encyclopedia of Neuroscience. Elsevier.

Smith, C. N. Hopkins, R. O., & Squire, L. R. (2006) Experience-dependent eye movements, awareness, and hippocampus-dependent memory. Journal of Neuroscience, 26(44), 11304-11312.

Cheng, D. T., Knight, D. C., Smith, C. N., & Helmstetter, F. J. (2006). Human amygdala activity during the expression of fear responses. Behavioral Neuroscience, 120(6), 1187-95.

Gold, J. J., Smith, C. N., Bayley, P. J., Shrager, Y., Brewer, J. B., Stark, C. E. L., Hopkins, R. O., Squire, L. R. (2006). Item memory, source memory, and the medial temporal lobe: Concordant findings from fMRI and memory-impaired patients. Proceedings of the National Academy of Sciences, 103(24), 9351-9356.

Smith, C. N. & Squire, L. R. (2005). Declarative memory, awareness, and transitive inference. Journal of Neuroscience, 25(44), 10138-46.

Smith, C. N., Clark , R. E., Manns, J. R., & Squire, L. R. (2005). Acquisition of differential delay eyeblink classical conditioning is independent of awareness. Behavioral Neuroscience, 119(1), 78-86.

Knight, D. C., Cheng, D. T, Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2004). Human amygdala and hippocampal activity during acquisition and extinction of fear conditioning. Cognitive, Affective, and Behavioral Neuroscience, 4(3), 317-25.

Knight, D. C., Cheng, D. T, Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2004). Neural substrates mediating human delay and trace fear conditioning. Journal of Neuroscience, 24(1), 218-28.

Cheng, D. T., Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2003). Functional MRI of human amygdala activity during pavlovian fear conditioning, stimulus processing versus response expression. Behavioral Neuroscience, 11(1), 1-12.

Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (1999). Functional MRI of human pavlovian fear conditioning: Patterns of activation as a function of learning. Neuroreport, 10, 3665-3670.

Contact Info

Phone

(858) 642-3628

Fax

(858) 552-7457

E-mail

cnsmith@ucsd.edu

Location

Room 340

Stein Clinical Research Building

University of California, San Diego

Regular Mail

Veterans Affairs Medical Center

116A 3350 La Jolla Village Dr.

San Diego, CA 92161-2002

Overnight Mail

University of California, San Diego

340 Stein Clinical Research Building

La Jolla, CA 92093