C. Brock Kirwan, PhD

Postdoctoral Fellow 3350 La Jolla Village Drive (116A)
Memory Research Laboratory San Diego, CA 92161
Institute for Neural Computation Phone: (858) 642-3628
Postdoctoral Mentor: Larry Squire Fax: (858) 552-7457
University of California, San Diego  Email:


Research | Publications | Teaching | CV (pdf)

Education

Ph.D.

Johns Hopkins University: Psychological and Brain Sciences

2006

M.A.

Johns Hopkins University: Psychology

2004

B.S.

University of Utah: Psychology, cum laude

2001

B.S.

University of Utah: Philosophy, cum laude

2001

Research Interests (for details, please click here)

Broadly: Cognitive Neuroscience of Memory
Specifically: How does the brain form and retain distinct memories for things as mundane as what you had for breakfast, as well as more significant evens such as one's wedding? Furthermore, how does the system that forms and retains these memories interact with other cognitive abilities?
 

Research Experience

Postdoctoral Research: Institute for Neural Computation, University of California, San Diego (Research Adviser: Larry Squire).

2006-present

Doctoral Research: Department of Psychological and Brain Sciences, Johns Hopkins University (Doctoral Advisor: Craig Stark)

2002-2006

Undergraduate Honors Research: Department of Psychology, University of Utah (Honors Thesis Advisor: Raymond Kesner)

1999-2001

Publications

Kirwan, C.B., Wixted, J.T., & Squire, L.R. (In Press).  Activity in the medial temporal lobe predicts memory strength, whereas activity in the prefrontal cortex predicts recollection. The Journal of Neuroscience.

Shrager, Y., Kirwan, C.B., & Squire, L.R. (2008). Activity in both hippocampus and perirhinal cortex predicts the memory strength of subsequently remembered information. Neuron, 59:547-533. [link, commentary]

Shrager, Y., Kirwan, C.B., & Squire, L.R. (2008). The neural basis of the cognitive map: Path integration does not require hippocampus or entorhinal cortex. Proceedings of the National Academy of Sciences, 105(33):12034-12038. [link, press]

Bakker, A., Kirwan, C.B., & Stark, C.E.L. (2008). Pattern separation in the human hippocampal CA3 and dentate gyrus. Science. 319:(5870):1640-1642. [link]

Kirwan, C.B., Galvan, V.V., Bayley, P.B., & Squire, L.R. (2008). Detailed Recollection of Remote Autobiographical Memory After Damage to the Medial Temporal Lobe. Proceedings of the National Academy of Sciences. 105(7):2676-2680. [pdf] [press 1, press 2]

Kirwan, C.B., Jones, C.K., Miller, M.I., & Stark, C.E.L.  (2007).  High-Resolution fMRI Investigation of the Medial Temporal Lobe. Human Brain Mapping 28(10):959-966. [pdf]

Kirwan, C.B., & Stark, C.E.L. (2007).  Pattern separation processes in the human medial temporal lobe: an fMRI investigation. Learning and Memory 14:625-633. [pdf]

Kirwan, C.B., Gilbert, P.E., & Kesner, R.P. (2005).  The role of the hippocampus in spatial location retrieval. Neurobiology of Learning and Memory 83(1):65-71. [pdf]

Kirwan, C.B., & Stark, C.E.L.  (2004).  Medial temporal lobe activation during encoding and retrieval of novel face-name pairs. Hippocampus 14:919-930. [pdf]

Invited Presentations

"High-resolution fMRI Investigation of Pattern Completion & Pattern Separation in the Medial Temporal Lobe" Invited talk presented at Stanford University 4/16/08.

"A Method for Achieving Greater Cross-Participant Alignment for MTL Structures" Invited talk presented at San Diego State University 3/14/08.

"The Effect of Memory Strength Manipulations in the Medial Temporal Lobe" Invited talk presented at Pázmány Péter Katolikus Egyetem (Pázmány Péter Catholic University), Budapest, Hungary, 2/22/08.

"Memory and Amnesia" Invited lecture to the Brain Myths course of the Discover Hopkins Pre-College Summer Program at Johns Hopkins University, 7/9/07.

"Overcoming interference: Pattern separation processes in the medial temporal lobe" Invited talk presented at San Diego State University 11/17/06.

Abstracts and Conference Talks

Kirwan, C.B. and Squire, L.R. (2008). The medial temporal lobe responds to memory strength but not recollection and familiarity. Poster presentation at the Annual Inter-Science of Learning Center Student and Post-Doc Conference, Pittsburgh, PA, February 2008.

Kirwan, C.B., Shrager, Y., & Squire, L.R. (2007). Medial temporal lobe activity varies with strength of subsequent recognition memory.  Society for Neuroscience Abstracts, vol. 33, Program No. 526.10.

Bakker, A., Kirwan, C.B., Miller, M.I., & Stark, C.E.L. (2007).  Pattern separation in the human hippocampal CA3 and dentate gyrus subfields.  Society for Neuroscience Abstracts, vol 33, Program No. 667.2.

Kirwan, C.B., Stark, S., Goodrich-Hunsaker, N., Gordon, B., Hopkins, R., & Stark, C.E.L. (2007). Pattern separation processes in the human medial temporal lobe. Poster presentation at the Cognitive Neuroscience Society 14th Annul Meeting, New York, May 2007.

Kirwan, C.B., & Stark, C.E.L. (2006).  High-resolution fMRI investigation of pattern completion and pattern separation in the medial temporal lobe: Evidence of dissociation.  Society for Neuroscience Abstracts, vol. 32, Program No. 777.10.

Kirwan, C.B., Flanery, M.A., Jones, C.K., Pekar, J., & Stark, C.E.L. (2005).  High-resolution fMRI investigation of the medial temporal lobe.  Society for Neuroscience Abstracts, vol. 31, Program No. 315.11.

Kirwan, C.B., & Stark, C.E.L.  Medial temporal lobe activation in a cued recall fMRI paradigm.  Poster presentation at the Cognitive Neuroscience Society 11th Annual Meeting, San Francisco, April 2004.

Kirwan, C.B., & Stark, C.E.L.  Medial temporal lobe activation in encoding and retrieval of novel face-name pairs.  Poster presentation at the International Neuropsychological Society 32nd Annual Meeting, Baltimore, Feb. 2004.

Kirwan, C.B., & Stark, C.E.L.  (2003).  Medial temporal lobe activation in encoding and retrieval of novel face-name pairs.  Society for Neuroscience Abstracts, vol. 29, Program No. 514.7.

Kirwan, C.B., Gilbert, P.E., and Kesner, R.P.  (2001).  The role of the hippocampus in spatial pattern completion.  Society for Neuroscience Abstracts, vol. 27, Program No. 315.3.

Kirwan, C.B., Gilbert, P.E., & Kesner, R.P. The role of the hippocampus in spatial pattern completion.  Poster presentation at the Intermountain Chapter of the Society for Neuroscience Fall Meeting, Lehi, UT, Oct. 2001.

Awards and Honors

  • Institutional National Research Service Award, Institute for Neural Computation Training Grant, University of California, San Diego

2006-2008

  • National Science Foundation Graduate Research Fellowship Honorable Mention

2004

  • Faculty for Undergraduate Neuroscience Travel Award

2001

  • National Science Foundation Research for Undergraduate Education (RUE) supplemental award

2000

  • National Merit Scholar, University of Utah

1995-2000

Courses Taught
(evaluations available upon request)

Cognitive Psychology
San Diego State University

Summer 2008 Spring 2008
Fall 2007

  • In this large, upper-division survey course, I cover a number of topics related to cognitive psychology and cognitive neuroscience, including sensation, perception, memory, attention, motor control, and decision making. 

 

Statistical Methods in Psychology
San Diego State University

 

Fall 2007
Spring 2007

  • I have taught this requirement for the psychology major at SDSU for two semesters.
  • I designed the syllabus to integrate with a separate lab section.
  • To engage students in this admittedly dense topic, I use a number of techniques, including small group activities, video demonstrations, and in-class experiments.

Brain Myths: Neuroscience in Popular Culture and the Media
Johns Hopkins University

Intersession 2006
Intersession 2005

  • I developed this course as a short introduction to Cognitive Neuroscience using various media (movies, magazine articles, online forums) as a gateway to the scientific literature.
  • I conceived and proposed the course, wrote the syllabus, wrote and delivered lectures, and performed all grading duties.

Laboratory in the Analysis of Psychological Data
Johns Hopkins University

Spring 2005

  • This is research methods and statistics course required for all Psychology majors at Johns Hopkins. 
  • I functioned as primary instructor for one of four sections. 
  • My duties included collaborating with other section leaders to write exams and weekly quizzes as well as organize in-class labs, writing and delivering lectures, advising students on their required research projects, and all grading.

Teaching Assistant Experience

Johns Hopkins University:

Spring 2006

Cognitive Neuroscience of Memory

Fall 2005 History of Psychology
Fall 2004 Mental Models & Mental Logic
Spring 2004 Functional Human Neuroanatomy
Fall 2003 Introduction to Psychology
Spring 2003 Behavioral Medicine
Fall 2002 Physiological Psychology

University of Utah:

Fall 2001 Brain and Behavior
Spring 2001 Brain and Behavior

Other Teaching Experience

Supplemental Instruction Leader for Introduction to Psychology at the University of Utah

Fall 2001

Spring 2002

  • Supplemental Instruction (SI) is a program offered through the Tutoring Center at the University of Utah whereby students can gain access to additional help in selected courses.
  • SI leaders are advanced undergraduates selected through a competitive application and interview process.
  • Duties included attending course lectures, organizing and conducting several weekly review sessions. 

 

Professional Affiliations

Society for Neuroscience
Cognitive Neuroscience Society
 

University and Community Service

Institute for Neural Computation Fellows Seminar Organizer

2007-2008

UCSD Center for Functional MRI Users Meeting Organizing Committee
2007-2008

Brain Awareness Presentation at Show Low High School, Show Low, AZ

2007

Brain Awareness Week presentation at Baltimore Polytechnic High School, Baltimore, MD

2004-2006

Department Representative to the Graduate Representative Organization, Johns Hopkins University

2003-2004

Volunteer Assistant to the Hungarian National Olympic Committee at the 2002 Salt Lake Winter Olympic Games

Feb. 2002

Ad Hoc Reviewer

Brain, Brain Research, Cerebral Cortex, Hippocampus


Last updated:9/9/08
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